Principal Investigator

Andrew Goldstein, Ph.D., is an Assistant Professor-In-Residence in the departments of Urology and Molecular, Cell & Developmental Biology, and a member of the Broad Stem Cell Research Center and Jonsson Comprehensive Cancer Center at UCLA. Dr. Goldstein attended Dartmouth College in Hanover, New Hampshire where he majored in Biochemistry and Molecular Biology and was a two-time NCAA Division 1 All-American lacrosse player. Dr. Goldstein moved to UCLA where he completed his Ph.D. in the laboratory of Dr. Owen Witte, isolating epithelial progenitor cells from mouse and human prostate tissue and demonstrating the capacity of progenitor cells to respond to oncogenic transformation. This work included the first demonstration of a cell of origin for human prostate cancer reported in Science Magazine. In 2011, Dr. Goldstein became the Inaugural fellow of the Broad Stem Cell Research Center and received a Prostate Cancer Foundation Young Investigator Award and a Department of Defense Prostate Cancer Research Program Idea Development Award to elucidate the cellular and molecular mechanisms promoting epithelial cancer initiation, progression and resistance to treatment.

 

STUDENTS

 

Preston Crowell is a graduate student in UCLA's Molecular Biology Interdepartmental Program (MBIDP), entering through the Cell & Developmental Biology (CDB) home area. Preston is studying the role of metabolic pathways in prostate progenitor cells and tumorigenesis.

 

 

 

 

Hector Navarro is a graduate student in UCLA's Molecular Biology Interdepartmental Program (MBIDP), entering through the Cell & Developmental Biology (CDB) home area. Hector is investigating mechanisms of oncogenic transformation  in prostate cancer.

 

 

 

Jonathan Fox is an undergraduate majoring in Molecular, Cell & Developmental Biology with a minor in Biomedical Research. In the laboratory, Jonathan is characterizing immune cells in the prostate using mass cytometry. At the 2017 MCDB Departmental Retreat, Jonathan took home the Best Poster Prize in the Undergraduate category.

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Johnny Diaz is an undergraduate majoring in Molecular, Cell & Developmental Biology with a minor in Biomedical Research. Johnny is supported by a UCLA Center for Academic & Research Excellence (CARE) Scholarship to investigate the effects of distinct oncogenes and oncogene combinations on prostate epithelial cells.

 

 

 

 

 

Ana Cabrera is an undergraduate majoring in Microbiology, Immunology & Molecular Genetics. Ana is studying the role of NAD+ metabolism in prostate cancer.

 

 

 

RESEARCHERS

 

 

Takao Hashimoto, M.D., Ph.D. is a Staff Research Associate and lab manager. Takao works on multiple projects in the lab and is generating new lentiviral vectors to study the role of oncogene combinations in prostate cancer.

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